Multidrop Combi Reagent Dispenser

The Thermo Scientific™ Multidrop™ Combi reagent dispenser offers unrivalled levels of performance, versatility and simplicity for biotech, pharmaceutical, and QC laboratories. For high-throughput screening, the Multidrop Combi dispenser dispenses into 1536-well plates at nanoliter levels with minimal dead volume.

At the other end of the scale, being able to dispense at volumes up to 2500 μl offers biotech researchers a wider range of applications. Add full robotic capability, and the Multidrop Combi dispenser is your answer for effortless, high-throughput bulk dispensing.


Life Science, Lab Equipment, Animal health

Thermo Scientific

Plate types : 6-, 12-, 24-, 48-, 96-,384-, 1536-well plates (plate height 5–50 mm)
Dispensing volume range : 0.5–2500 μl
Dispensing precision (CV%) : Small tube dispensing cassette:
0.5 μl: CV≤10%
2 μl: CV≤ 5%
10 μl: CV≤ 3%
>10 μl: CV≤ 3%
Standard tube dispensing cassette:
5 μl: CV≤ 10%
20 μl: CV≤ 1.5%
100 μl: CV≤ 1%
>100 μl: CV≤ 1%
Dispensing speed : 96-well plate: 10 μl in 3 seconds, 20 μl in 4 seconds, 100 μl in 10 seconds.
384-well plate: 1 μl in 5 seconds, 5 μl in 5 seconds, 10 μl in 6 seconds, 20 μl in 9 seconds
1536-well plate: 1 μl in 14 seconds, 5 μl in 26 seconds
Dispensing increments : Small tube dispensing cassette: 0.5 μl increments
Stand tube dispensing cassette: 5 μl increments
Dead volume : < 1 ml volume range 0.5–50 μl
< 7 ml volume range > 50 μl
Interface Serial RS-232, USB : Serial RS-232, USB
Overall dimensions : 220(H) x 355(W) x 330(D) mm
8.6(H) x 14(W) x 12.9(D) in.
Weight : 9.1 kg (20.1 lbs.)
Power requirements : 100–240 Vac, 50/60 Hz, nominal
Application : Assay Development

Primary and Secondary Screening

Compound Storage

Genomic and Proteomic Research (PCR and Sequence Setup)

Cell-based Assay


Wide range of solutions : Buffers




Viscous Solutions


  • Wide volume range – precise dis­pensing over a 0.5–2500 μl range, giving reproducible assay data
  • Any plate, any well size – from 6 to 1536 wells and plate heights of 5 to 50 mm – the Multidrop Combi dispenser works for virtually any application
  • Simple operation – the visual icon-based graphic display makes it easy to use and program, even without training
  • Reduced reagent costs – low volume dispensing, minimal dead volume and backflushing minimizes re-runs and usage of expensive reagents
  • Traceability – Multidrop Combi SMART dispenser automatically tracks cassette usage for improved reliability and traceability
  • Increased functionality – easy-to-use Thermo Scientific™ FILLit™ Software provides means to develop and transfer protocols into the instrument, as well as offering an extensive plate selection
  • High-throughput, 24/7 operation – full robotic compatibility gives increased throughput, backed up by the reliability of the Multidrop technology – proven in use with over 11,000 units installed worldwide
  • Reproducible dispensing of live cells with the Thermo Scientific Multidrop Combi reagent dispenser
Catalog no. Description
5840300 Multidrop Combi, 100–240 V 50/60 Hz
5840320 Multidrop Combi with SMART 2 option, 100–240 V 50/60 Hz

Includes cassette lifetime traceability feature

5188009 FILLit Software for Multidrop Combi
24073290 Small tube plastic tip dispensing cassette (for volumes 0.5–50 μl)
24073293 Long small tube plastic tip dispensing cassette (for volumes 0.5–50 μl)
24073295 Small tube metal tip dispensing cassette (for volumes 0.5–50 μl)
24073298 Long small tube metal tip dispensing cassette (for volumes 0.5–50 μl)
24073291 Small tube plastic tip dispensing cassette 5-pack
24073296 Small tube metal tip dispensing cassette 5-pack
24072670 Standard tube dispensing cassette (for volumes 5–2500 μl)
24072671 Standard tube dispensing cassette 5-pack
24072672 Standard tube dispensing cassette 10-pack
24072677 Long standard tube dispensing cassette (length of tubing 50–200 cm in 10 cm increments)